Vascular endothelial growth factor significance

Vascular endothelial growth factor is a glycoprotein that is significant in promoting angiogenesis and can promote vascular endothelial cell movement, proliferation, and division, which has important physiological and pathological significance. The physiological significance mainly includes the promotion of tissue growth, and for infants and adolescents, it provides some vascular growth guarantee. In adults, the angiogenesis-promoting effect of VEGF is also significant for certain physiological states, for example, in pregnancy state, angiogenic factor can promote placental angiogenesis and provide some guarantee for fetal growth. The significance in pathological states include: because vascular endothelial growth factor can promote the growth of blood vessels, it plays a role in the occurrence and development of certain diseases such as tumors, and correspondingly inhibiting the growth of vascular endothelium can inhibit the development of tumors. The expression of vascular endothelial growth factor is also more in the process of tissue injury healing, which promotes tissue healing and growth.