Palm itching and tightness may be related to herpes sweat, hand eczema, contact dermatitis and other diseases. 1. Sweat herpes: sweat herpes patients skin will appear blisters, itching and other symptoms, blisters dry peeling, will be accompanied by pain, some patients will appear palms itchy tight symptoms. The cause of its formation may be triggered by factors such as dermatophyte infection, mental as well as allergy. 2. Hand eczema: the patient’s fingers, palms and other places may appear blisters, peeling, cracking and so on, will be accompanied by itching, pain. If you suffer from hand eczema, you may feel itchy and tight in the palm of your hand. The cause of its formation may be caused by allergies, infections and genetic factors. 3. Contact dermatitis: contact dermatitis patients will appear red, swollen, painful and itchy skin, some patients may also appear tightness. The cause is mostly related to skin contact with irritating and allergic substances. The cause of the itching and tightness of the palms of the hands is not one, it is recommended that patients go to a regular hospital to clarify the cause of the disease.