The slow healing of penile epidermal ulcers may be caused by genital herpes, syphilis, circumcision and glans penis, etc., and the cause should be identified by timely consultation. 1. Genital herpes often presents a chronic, recurring process, and is usually difficult to cure, recurrence is related to some triggering factors, such as alcohol, spicy food, fatigue, colds, anxiety, stress, sexual intercourse, etc.; the main manifestation of the genital area blisters, pain, itching or ulcers. 2. Syphilis is a chronic sexually transmitted disease caused by the syphilis spirochete that invades multiple systems, when the pathogen is still latent in the body, it is still infectious, or intermittent episodes of the situation. Syphilis rash may appear as pustules (elevations on the skin which contain pus), ulcers, sores, etc. in the skin and mucous membranes of the mouth, throat or genitals. 3. When the foreskin glans inflammation heavy may appear ulcers, vesicles, and even bleeding, long time does not heal may be the local presence of drug-resistant bacteria infection, or the presence of the body’s immune system is lowered and so on. In summary, it is recommended that the patient timely consultation, the doctor to clarify the reasons for the long non-healing, to take targeted treatment.