If Down’s syndrome screening in early pregnancy indicates a high risk, it is recommended that the pregnant woman undergo further amniocentesis or non-invasive DNA testing for a definitive diagnosis. A high risk of Down’s syndrome screening indicates a high probability of the fetus having Down’s syndrome, but there is no certainty of having Down’s syndrome. Amniocentesis and non-invasive DNA tests are more than 99% accurate, but amniocentesis has a high risk factor and requires hospitalization in a large hospital for the test. Non-invasive DNA is a non-invasive blood test that does not cause trauma to the fetus or the pregnant woman, and has a higher accuracy rate for diagnosing Down syndrome. Pregnant women can choose according to their own situation, and also decide to keep the fetus under the guidance of the doctor according to the results. It is recommended that pregnant women should have the appropriate checkups on time during pregnancy and undergo Down’s syndrome screening at 16-18 weeks of pregnancy to avoid congenital defects in the fetus and to achieve eugenics.