The difference between HPV bivalent (vaccine), quadrivalent vaccine and nine-valent vaccine lies in the price and the difference in the type of HPV virus to be prevented. 1. Price: the price of bivalent vaccine is relatively low, with the increase in the number of valence, the price is also increased, the nine-valent vaccine is generally the most expensive. 2. Prevent the type of HPV virus: bivalent vaccine to prevent two kinds of viruses, including HPV16, 18 types of viruses, is the most critical two subtypes, is to lead to cervical cancer and warts of the main reason. Quadrivalent vaccine prevents four viruses, including HPV16, 18, 6, 11. Nine-valent vaccine prevents nine viruses, including HPV16, 18, 6, 11, 31, 33, 45, 52, 58, which increases the intensity of the prevention of cervical lesions and condyloma acuminatum. It is recommended to choose the vaccination according to your personal situation under the guidance of your doctor.