There is no good or bad for the elderly to take aspirin, only the right or not. If the elderly have atherosclerosis or cardiovascular and cerebrovascular risk, in the exclusion of contraindications under the premise of the physician’s guidance can be applied aspirin, can play an anti-atherosclerosis role to delay the risk of coronary heart disease and cerebrovascular disease. Aspirin, as a more widely used antiplatelet drug, can inhibit the enzyme cyclooxygenase and reduce the production of thromboxane and prostacyclin, which have the effect of promoting platelet aggregation and vasoconstriction. Small-dose aspirin only inhibit thromboxane generation, no effect on prostacyclin, so it has the role of anti-platelet aggregation and prevention of thrombosis, aspirin is easy to absorb orally, but the use of large doses of gastric stimulation, and even lead to bleeding, so do not recommend that the elderly take aspirin for a long time, long-term use of aspirin may appear gastric ulcers, or their own bleeding is not easy to stop bleeding. Aspirin only belongs to the prevention of cardiovascular and cerebrovascular diseases, the elderly if clearly suffering from cardiovascular and cerebrovascular diseases, such as transient ischemic attack, myocardial infarction, atrial fibrillation, arteriovenous fistula, cerebral infarction, etc., it is recommended that the use of aspirin as a secondary preventive medicine. If it is only used as a prophylactic drug to prevent cardiovascular and cerebrovascular diseases, it is not recommended for long-term use in older patients.