Mesalazine suppositories can be used once a day for a long time when there are indications for the drug. Specific use of the drug is subject to medical advice. After the use of mesalazine suppository, can arrive at the mucosa of the inflammatory part of the colon disease, thus inhibiting the synthesis of prostaglandins and the formation of inflammatory mediators leukotrienes, mainly used for ulcerative colitis, Crohn’s disease and other diseases of the treatment; and the above diseases need to be a long-term medication in order to achieve a better therapeutic effect, generally need to be 8 to 12 weeks. Usually the drug may cause stomach discomfort, headache, dizziness and other discomforts after use; allergic to the components of the drug, salicylic acid drugs and excipients, severe liver and kidney function impairment, children under 2 years of age are prohibited; liver and kidney function need to be monitored in the process of taking the drug, and for pregnant women, lactating mothers, the elderly and other special groups of people, the need to use the drug under the guidance of a doctor. If you need to use Mesalazine suppository for a long time due to the condition, it is recommended to decide the dosage and learn the precautions after the doctor’s comprehensive assessment of the condition.