The edema and blisters of the feet may be the cause of tinea pedis, atopic dermatitis and herpes sweat, etc. The method of reducing swelling is mainly to give antifungal, antiallergic, and antipruritic and antiperspirant medication. 1. Tinea pedis is due to the foot part of the skin infection ringworm and the formation of a disease, in which the blister type of tinea pedis is mainly manifested in the palms of the feet, toes and both sides of the skin edema with blisters, in the treatment of boric acid solution can be used externally wet compresses, and at the same time comply with the doctor’s instructions oral itraconazole dispersible tablets or terbinafine tablets for antifungal treatment. 2. Allergic dermatitis is a kind of perverse reaction that occurs when the skin is stimulated by some external factors, which can be manifested as blisters, vesicles and itching in the clinic, etc. In the treatment of glucocorticosteroid creams, such as Dinocap, mometasone furoate, etc., the use of anti-allergy treatment is prescribed by the doctor. 3. Sweat herpes is also called sweating bad eczema, the cause of its pathogenesis and a variety of external factors related to stimulation, in the clinical mainly manifested in the palms of the palms of the feet and palms of the parts of the skin edema accompanied by itchy blisters, in the treatment of prescribed use of glycerine lotion and other astringent anti-itching medication can be relieved, but also can be combined with oral loratadine tablets and other anti-itching drug therapy. All of the above drugs should be used in accordance with medical advice. There are many other reasons for edema and blisters on the soles of the feet, and it is recommended to go to a regular hospital to get a clear picture of the cause of the problem and use medication under the guidance of the doctor.