Recurrent asthma attacks seriously affect quality of life One day, a middle-aged woman came to the asthma clinic with a “KeXing” face, shortness of breath and a painful appearance. Upon asking her medical history, it turned out that this patient had been suffering from recurrent asthma attacks for 8 years, going to the emergency room for intravenous dexamethasone during acute attacks and taking prednisone intermittently during the week. Due to the long-term intravenous and oral hormones, Coxing face and osteoporosis appeared, but asthma attacks were still frequent, so much so that he was on long-term sick leave to rest at home Asthma patients can be treated with systemic hormones during acute attacks, but systemic hormones should be withdrawn as early as possible after the acute attack period and replaced with inhaled hormones for long-term control treatment. This can achieve asthma control, reduce or prevent attacks, and avoid the side effects of using intravenous or oral hormones during an attack. In this patient, the usual maintenance control treatment with inhaled hormones was not used, so it led to recurrent asthma attacks and therefore led to serious consequences. Another patient, with a 20-year history of asthma, used only aminophylline and Bolicamni during asthma attacks and went to the emergency room for intravenous aminophylline and dexamethasone when the shortness of breath became severe, often waking up at night from sleep and moving during the day with shortness of breath. Asthma attacks seriously affected sleep and quality of life, and the young man of 25 looked like a little old man in his 50s. Asthma is a chronic inflammatory disease of the airways. Even if asthma attacks do not usually occur, the inflammation of the airways persists, so asthma treatment is long-term and should be maintained with inhaled hormonal anti-inflammatory drugs for a long time. In contrast, this patient usually used only oral wheezing medication without anti-inflammatory drugs, resulting in uncontrolled asthma, which seriously affected the quality of life. Later, both patients were switched to salmeterol fluticasone as long-term control therapy and given Ventolin aerosol on demand, with significant improvement in symptoms, reaching complete control after 3 months. Two types of medications must be kept in mind Currently, the main types of medications used to treat asthma are control medications and relief medications. Control medications include anti-inflammatory medications and long-acting bronchodilators, which require long-term, daily use. The most commonly used anti-inflammatory drugs are inhaled glucocorticosteroids, such as bicodone, promethazine, and co-codone. As a long-term control medication, it is not effective when used during an attack and only becomes therapeutic after a week. However, it is an indispensable drug for repairing airway inflammation and needs to be used consistently for a long time to reduce or prevent asthma attacks. Research data prove that inhaling hormones under the guidance of doctors is very safe and will not affect the growth and development of children, nor will it bring side effects such as hormone dependence and osteoporosis to adult patients. The safest and most effective of the long-acting bronchodilators are inhaled long-acting beta2 agonists, which are also used for long-term control, and others are extended-release theophylline and oral long-acting beta2 agonists. Relieving drugs are rapid relief of airway spasm, also known as emergency drugs, including inhaled short-acting beta2 agonists, inhaled anticholinergics, short-acting theophylline and short-acting oral beta2 agonists, and systemic glucocorticoids, which are mainly used during acute asthma attacks and can be effective in a few minutes to relieve airway constriction symptoms. Nowadays, the most commonly used are inhaled short-acting beta2 agonists such as salbutamol aerosol. For each asthma patient, if the patient is a persistent asthmatic, he or she should be treated with regular daily controlled medication, such as inhaled glucocorticosteroids, and the doctor will give different doses of the medication according to the severity and grading of the patient’s condition. At the same time, you should also have relief medications, such as inhaled short-acting beta2 agonist – Ventolin aerosol, to use whenever you have symptoms to relieve shortness of breath, etc. However, it should be noted that the use of inhaled short-acting beta 2 agonist should not exceed 10 sprays a day. If a patient uses relief medication with increased frequency, it may suggest that the patient is having problems with asthma control and should consult a physician to adjust the dose of control medication such as inhaled hormones, etc. depending on the condition. Combination therapy is effective Currently, experts advocate that combination medication, i.e., a combination of inhaled glucocorticoids and inhaled long-acting beta 2 agonists, should be preferred for all asthma patients with class II or higher. The combination of these two types of control drugs can improve both anti-inflammatory and airway smooth muscle dysfunction, while the synergistic effect between the two can reduce the dose of inhaled hormone but increase the efficacy, playing a 1 + 1 > 2 effect, so that asthma symptoms can be better controlled. Salmeterol fluticasone is an effective drug that combines an inhaled glucocorticoid and an inhaled long-acting β2 agonist in a single inhalation device. The results of the recent international multicenter clinical study GOAL (Gaining Optimal Control of Asthma) showed that patients with mild, moderate and severe asthma treated with salmeterol fluticasone, compared to a single inhaled hormone, used a lower hormone dose to get better asthma control. As long as the long-term regular inhalation of sulforaphane can be adhered to, nearly half of the patients can achieve complete control and more than 80% of the patients can be well controlled and live, study and work like normal people. It should be said that this study has brought hope to 300 million asthmatics worldwide, so that all asthmatics are expected to live a normal life.