The price of tenofovir disoproxil fumarate tablets varies according to manufacturers, packaging specifications, sales channels, etc. There is no uniform pricing in the market at present, and it is usually around 40 to 500 yuan a box. The drug forms tenofovir diphosphate through the phosphorylation of cellular enzymes, which can terminate DNA synthesis, thus inhibiting the activity of HIV-1 reverse transcriptase and HBV reverse transcriptase. Therefore, the drug is clinically used for the treatment of adults with HIV-1 infection and chronic hepatitis B patients aged 12 years and above. During the use of the drug there are adverse reactions such as abdominal pain, muscle weakness, neurologic edema, rash. It is contraindicated in patients with a previous hypersensitivity to any of the components of this drug. Patients with HBV infection who discontinue tenofovir disoproxil fumarate therapy must be monitored closely; all HBV-infected patients should be screened for HIV-1 antibodies prior to initiating tenofovir disoproxil fumarate therapy. If you need to use the drug, please consult a specialist and buy it from a hospital or regular pharmacy.