Small blisters on the nose may be related to herpes simplex, contact dermatitis, chickenpox and other causes. 1. Herpes simplex: skin infection with herpes simplex virus in the nose area can cause blisters to appear on the infected area of the skin, accompanied by itching and pain. 2. Contact dermatitis: If you use allergen-containing nasal strips on your nose, it can cause a localized inflammatory reaction, which is manifested as skin pimples or herpes papules. 3. Chickenpox: the skin in the nose area is infected by chickenpox-herpes zoster virus, which can also cause local skin erythema, papules and blisters. It is recommended that people with small blisters on the nose go to the hospital in a timely manner to clarify the cause of the disease and standardize the treatment under the guidance of the doctor to avoid delaying the condition.