Impetigo, known clinically as impetigo, is a common purulent infectious skin disease that is highly contagious and can be epidemic in outbreaks, caused by Staphylococcus aureus or Streptococcus b haemolyticus infection. There is no set pattern for the treatment of impetigo, which is mainly treated with topical medications or oral antibiotics, and if the blisters are large, local disinfection is required to aspirate the blister fluid. Patients usually need to follow medical advice to choose topical medications, which commonly include roxithromycin ointment or mupirocin ointment. If the lesions are accompanied by fever, oral antibiotics such as penicillin, amoxicillin or other antibiotics can be used depending on the patient’s drug sensitivity. In addition, if the skin lesions are large and the situation is more serious, it is recommended that patients go to the hospital in a timely manner to avoid further deterioration of the disease. In particular, patients should be properly isolated to prevent contact infection, and contaminated clothes, towels and utensils should be disinfected. At the same time, attention should be paid to personal hygiene, keeping the skin clean and avoiding cold and spicy food. In the hot summer, children should bathe regularly and cut their nails regularly.