Methylprednisolone belongs to the glucocorticoid hormone, and the irrational use of hormones can bring many harms. It is recommended to use the drug correctly under the guidance of a doctor. Overdose of Methylprednisolone may affect many systems of the body: immune system abnormalities, allergic reactions; endocrine system abnormalities, Cushing’s syndrome, metabolic acidosis, etc.; mental, affective disorders, confusion, etc.; neurological abnormalities, intracranial pressure increase syndrome, etc.; reproductive system, menstrual disorders. The use of methylprednisolone affects many organs in the whole body: eye abnormalities, cataracts, glaucoma, etc.; cardiac abnormalities, congestive heart failure, tachycardia, etc.; lung abnormalities, pulmonary embolism; gastrointestinal system abnormalities, gastric hemorrhage, peptic ulcers, etc.; musculoskeletal abnormalities, necrosis of the femoral head, muscle atrophy, etc.. In addition, the irrational use of methylprednisolone will also lead to a number of laboratory test results abnormal, blood alkaline phosphatase increased, increased intraocular pressure, decreased glucose tolerance, decreased blood potassium, increased urinary calcium, blood urea increased and so on. Therefore, Methylprednisolone Tablets should be used with reasonable caution in accordance with medical advice, and should not be abused as glucocorticosteroids.