Blood cancer usually refers to leukemia, and the clinical manifestations of advanced stage of blood cancer are as follows: I. Severe anemia symptoms. In advanced stage of leukemia, due to the leukemia cells seriously destroying the hematopoietic function of the human body, coupled with long-term chemotherapy, malnutrition and other factors, the patient will suffer from severe anemia, which will be manifested as obvious pale face like white paper, and at the same time, obvious fatigue, and sometimes unable to get out of bed. In severe cases, there will be panic, chest tightness, even in a quiet state, panic, chest tightness. Second, the symptoms of infection, most of the leukemia patients, the late stage will appear obvious symptoms of high fever, often high fever, given a variety of antibacterial drugs is not obvious, even if given antipyretic drugs can only briefly reduce the body temperature. Third, obvious bleeding symptoms, will be manifested as obvious bleeding spots on the skin and mucous membranes, petechiae, nasal cavity gums and internal bleeding, and in severe cases, craniocerebral hemorrhage will occur, resulting in the death of the patient.