Blood leaving the veins is the clinical manifestation of crush syndrome. Squeezing syndrome is when a person is buried by a stone and earth, especially a limb with rich muscles is squeezed for more than one hour (such as the thigh), and then causes a series of pathological changes in the body due to damaged skin and flesh, blood leaving the vasculature, stasis of blood accumulation, stagnation of qi and blood, meridian occlusion, local pain, swelling of the limb, indentation and hardening of the skin, subcutaneous stasis of blood, and increased skin tension. What are the prevention methods for extrusion syndrome? Because the mortality rate of this syndrome is light higher, so prevention is the key, the general preventive measures are: 1, post-injury replenishment of lactic acid Ringer’s fluid and colloid fluid: replenishment as soon as possible after the injury, such as colloid fluid available plasma or dextrose, can be entered at 80-100ml of colloid fluid per 1% of the compressed area, every 1 hour of compression, 3-4ml of fluid per kilogram of body weight, plus the amount required for 24 hours 1500ml, calculated for the post-injury The first day of rehydration, later adjusted according to the situation, but if the occurrence of extrusion syndrome, it can not be rehydrated according to the above, and to control the amount of fluid infusion. 2, alkalinization of urine: because extrusion syndrome often has acidosis, so early that the application of alkaline drugs to alkalinize the urine to prevent acidosis, to prevent myoglobin and acidic urine action in the renal tubules deposition, can be oral sodium bicarbonate solution or intravenous input 5% sodium bicarbonate, given about 25-30 daily. 3, diuretic: when the blood pressure is stable, diuretic can be carried out, so that before the renal parenchyma is damaged, there is more alkaline urine through the renal tubules, increasing the excretion of harmful substances such as myoglobin, available 20% mannitol rapid intravenous input, its high osmotic pressure effect can increase the renal blood flow, so that the glomerular filtration rate increases, the renal tubules remain filled, reduce interstitial edema, prevent the precipitation of agglutinates in the renal tubules, so as to protect renal function. thus protecting renal function, so it is appropriate to apply early. 4, release renal vasospasm: after extrusion injury, the concentration of renin, histamine and other vasoconstrictive substances in the blood increases, making renal vasoconstriction spasm, early use of mannitol at the same time can add vasodilators to release renal vasospasm, increase renal blood flow. 5, cut the fascia decompression release exudate, improve circulation: incision should be in the most serious parts of muscle swelling, long beyond the swollen area without probing deep, for the limb of muscle necrosis, once the appearance of myoglobinuria or other signs of early renal failure, the decisive amputation.