Rheumatoid arthritis can be treated with antibiotics against streptococcal infections, such as benzylpenicillin and roxithromycin. Rheumatoid arthritis is a type of reactive arthritic disease caused by human infection with group A beta-hemolytic streptococcus, so it is necessary to use antibiotic treatment for streptococcal infections, commonly used drugs for penicillin (such as benzylpenicillin, procaine penicillin), penicillin allergy can be changed to use cefotezole, roxithromycin, lincomycin and so on. The treatment of rheumatoid arthritis is aimed at removing the cause of the disease, eliminating the streptococcal infection foci, antirheumatic therapy, and treating complications. Therefore, in addition to antibiotic treatment, it is also necessary to use glucocorticoids (such as prednisone), non-steroidal anti-inflammatory drugs (such as aspirin) for anti-rheumatic therapy, the use of risperidone, valproate and other drugs for chorea, and so on. The above drugs should be used under the guidance of a physician, and it is recommended that patients diagnosed with rheumatoid arthritis go to the rheumatology and immunology department of a regular hospital for detailed consultation.