The possible causes of sneezing and running nose in the morning are allergic rhinitis and vasomotor rhinitis. 1. Allergic rhinitis: mainly manifested as itchy nose, frequent sneezing and runny nose in the morning, the main cause of which is nasal allergic reaction caused by allergens, which can be treated by oral anti-allergic drugs, such as loratadine tablets, montelukast sodium tablets, and topical budesonide nasal spray. 2. Vasomotor rhinitis: it is a kind of non-allergic, non-infectious inflammation of nasal mucosa, which can be manifested as morning sneezing, runny nose, nasal itching and nasal congestion. Treatment is mainly to avoid the stimulation of adverse factors, such as temperature, emotion, etc.; medication, such as loratadine tablets, topical mometasone furoate; surgical treatment, suitable for patients with abnormal nasal structure. Wake up in the morning sneezing runny nose may also be caused by other reasons, such as upper respiratory tract infection, the patient should consult the doctor in time, to clarify the cause of the disease, early treatment, do not blindly use their own medication, so as not to delay the condition.