Gleason grading is the most widely used grading system for prostate cancer, and is based on a scale of 1-5, with the higher the degree of cell differentiation, the lower the score, and the better the prognosis. This system is based on the growth form of prostate cancer alveoli (which can be interpreted as a cluster of several prostate cancer cells in a vesicle-like structure) at fairly low magnification. . The Gleason score is the sum of the histological grade of the most common form of cancer growth plus the histological grade of the second most common form, which generally ranges from 2 to 10, with 1+1=2 for the best differentiation and 5+5=10 for the worst. For example, in a patient with prostate cancer, although there are small areas of cancer cells with grade 5 differentiation, the overall grade 1 differentiation is the most common, followed by grade 2 differentiation, the Gleason score is 3 and the prognosis is relatively good.