Cystic thyroid nodules grade 2 are usually benign, and those with small nodules and no obvious symptoms should be reviewed regularly. Those with hyperthyroidism or hypothyroidism can be treated with medication, while those with large nodules compressing the airways can be treated with surgery. It is recommended to follow the doctor’s advice. In the color ultrasound examination of the thyroid gland, thyroid nodules are divided into six grades, and the higher the grade, the higher the risk of thyroid cancer. Thyroid nodules graded at grade three or below have a higher probability of being benign, grade four or above may be malignant, and grade six can be determined to be malignant. If combined with hyperthyroidism, anti-thyroid drugs such as methimazole and propylthiouracil are needed. Combined with hypothyroidism requires long-term administration of levothyroxine. Surgery is needed if the nodule increases rapidly in size and symptoms of compression of the trachea, esophagus, or laryngeal reentry nerve occur. Thyroid cystic secondary nodules should be reviewed regularly and treated with medication or surgery as prescribed by the doctor.