Blackheads, also known as blackhead pimples or open pimples, and ointments to remove blackheads include retinoids, benzoyl peroxide and azelaic acid. 1. Vitamin A acids: Vitamin A acids include adapalene gel, tazarotene gel, and vitamin A ointment, which can dissolve acne, improve follicular sebaceous gland duct keratinization, and have anti-inflammatory effects at the same time. 2. Benzoyl peroxide: Benzoyl peroxide has a mild effect of dissolving acne, can be used alone, can also be combined with retinoic acid or topical antibiotics. 3. Azelaic acid: Azelaic acid also has the effect of dissolving acne, but also can reduce the skin surface, hair follicles and sebaceous glands within the bacteria, can be used for the treatment of blackheads. The use of drugs are required under the guidance of medical professionals to avoid adverse reactions.