Nephrogenic edema is mainly treated by diuresis to reduce edema, reducing proteinuria, and suppressing immune and inflammatory responses.
1. Diuresis: appropriate application of diuretics can control edema. Thiazide commonly used hydrochlorothiazide, medullary diuretics commonly used tachycardia, etc., the effect is powerful and rapid. In the case of pure use of diuretics is ineffective, can use albumin to improve the colloid osmotic pressure. Hydrochlorothiazide should not be taken by lactating women.
2. Reduce proteinuria: Persistent massive proteinuria can lead to glomerular hyperfiltration. Commonly used ACEI or ARB drugs such as captopril and irbesartan to lower blood pressure, reduce urinary protein and protect renal function.
3. Suppress immune and inflammatory reactions: glucocorticoids such as prednisone can be used, and cytotoxic drugs such as cyclophosphamide can also be used as appropriate. Long-term application of large doses of prednisone can cause medical hyperadrenocorticism, induce or aggravate infections, digestive system complications.
All of the above medications should be used under the guidance of a doctor, avoid self-medication. Patients with nephrogenic edema are advised to go to regular hospitals in a timely manner and receive standardized treatment under the guidance of a doctor.