Total cholesterol of 7.35 mmol/L is usually serious. Total cholesterol is mainly the value of the total amount of cholesterol contained in various lipoproteins in the blood, and it is able to assess the risk of coronary atherosclerotic heart disease and ischemic cerebrovascular disease. Usually the ideal range is <5.18mmol/L, the high range is 5.18~6.19mmol/L, and when ≥6.22mmol/L then it is in an elevated state, so total cholesterol of 7.35mmol/L has already reached the elevated range, which is usually more serious. It may be caused by diseases such as mixed hyperlipoproteinemia and familial hypercholesterolemia, which lead to mutations in enzymes related to lipoprotein metabolism and affect cholesterol metabolism. In addition, diseases such as diabetes mellitus, hypothyroidism, obstructive jaundice, etc., which cause abnormal lipid metabolism, cannot be ruled out. When the above symptoms appear, it is recommended to go to the hospital for consultation and early standardized treatment.