The 65 year old man, Ye, likes to smoke a pipe and has worked in the fields all his life. Half a year ago, a crusty nodule the size of a green bean grew on his lower lip, and the hardy old man didn’t care at first, but the small nodule slowly grew into a cauliflower-shaped swelling before the old man went to the hospital. After examination, the doctor found that the swelling covered 2/3 of the old man’s lower lip and was diagnosed as highly differentiated squamous cell carcinoma after taking biopsy. Since there was no enlarged lymph node metastasis in the jaw and neck of the old man, the doctor performed an extended lip cancer resection + lip repair, which not only removed the tumor from the old man’s lower lip, but also “reconstructed” the old man’s lower lip. Lip cancer is associated with smoking, sun exposure, local infection and irritation and chemical carcinogenic factors, especially for pipe smokers, so it is also known as “pipe cancer”. It occurs in men over 60 years old, mostly in the outer and outer 1/3 of the lower lip, and is mainly squamous cell carcinoma. Lip cancer grows slowly and usually has no conscious symptoms; in early stage, it often appears as herpes-like or crusty swelling, or local mucosal thickening, followed by crater-like ulcers or cauliflower-like swelling. The time of metastasis of lip cancer is generally late. Clinically, early stage lip cancer has good efficacy no matter it is treated by surgical excision, radiation therapy, laser therapy or cryotherapy; domestic data show that the 10-year survival rate of lip cancer patients can reach more than 75%. After the primary foci of lip cancer are removed, the lips can generally be repaired immediately with adjacent tissue flaps, thus “rebuilding” the lips and restoring the normal shape of lips. Therefore, elderly people over 60 years old who like to smoke pipes should be alert to “pipe cancer”, and if there are unhealed ulcers or crusted swellings on the lips, they should go to the hospital in time to avoid distant metastasis of cancer cells and delay the treatment.