Irritable bowel syndrome (IBS) is a gastrointestinal disorder characterized by prolonged, recurrent episodes of abdominal pain, bloating, abnormal bowel habits and stool characteristics, and mucus stools, and the lack of morphologic and biochemical abnormalities to explain the syndrome. It used to be called mucus enteritis, colonic spasm, colonic allergy, allergic colitis, and irritable colon. The disease is a common clinical condition, accounting for 20%-50% of gastrointestinal outpatient visits in Western countries, mostly in young and middle-aged people, and about twice as common in women as in men. Definition The definition of irritable bowel syndrome was proposed at the International Conference in Rome in 1988: 1. abdominal pain, relieved after defecation, or accompanied by changes in the shape and frequency of stool; 2. abnormal defecation behavior, manifested by two or more of the following: changes in the frequency of defecation, changes in the shape of stool, abnormal process of defecation, a sense of incomplete stool, and mucus stool. Typing The disease starts slowly, with intermittent episodes and periods of remission. Although there are individual differences in symptoms, the onset rules and forms are mostly fixed for a specific patient, and the age of onset is mostly between 20 and 50 years old. The disease can be divided into three types, namely diarrhea, constipation and mixed type. Clinical manifestations 1, abdominal pain: is the main symptom, mostly accompanied by abnormal defecation and relieved after defecation, some patients are easy to appear after eating, the following abdominal pain is common, the nature of pain is diverse, the degree varies. 2, diarrhea: characterized by low stool volume, often <200 g/day; diarrhea disappears after 72 hours of fasting; does not appear at night; about 1/4 patients can be triggered by eating; alternating diarrhea and constipation. 3, constipation: is a spastic constipation of the colon, manifested as lower abdominal pain and Yang stool-like constipation, diarrhea and constipation occurs after, mostly in the morning at 5-6 o'clock or after eating diarrhea, mostly mucus stool. After a period of time and turn to constipation, late can be persistent. 4, abdominal distension: aggravated during the day, reduced after sleep at night. 5.Extra-gastrointestinal symptoms: often accompanied by systemic mental symptoms, such as insomnia, forgetfulness, fatigue, headache, palpitations, feeling of dyspnea, frequent urination, urgent urination, sexual dysfunction or menstrual irregularities, etc. 6, psychiatric symptoms: the above symptoms appear or aggravate food, some patients have different degrees of psycho-psychiatric abnormal performance, such as depression, anxiety, paranoia, hostility, etc. Specific medication Because of the high degree of individualization of irritable bowel syndrome drug treatment, so must be under the medical advice of the choice of medication 1, antispasmodic agents, mostly used for patients with abdominal pain symptoms nifedipine - non-selective, with large side effects pivetonium bromide, oxybutynin - gastrointestinal selective: the current guidelines for abdominal pain is obvious 2, to promote power agents, mainly used for constipation, bloating patients Mosapride (currently commonly used intestinal power drugs) 3, laxative agents, used for patients with constipation Swelling laxatives - cellulose, etc. Dissolving laxatives - polyethylene glycol 4000 fosone Stimulating laxatives - phenolphthalein tablets, laxative Of course, the specific medication should be evaluated by a professional doctor according to the patient's clinical symptoms.