Herniated lumbar disc is particularly painful at night and mild during the day can be relieved by giving general treatment, medication, physiotherapy and surgery depending on the severity. The pain may be aggravated at night due to over-exertion during the day, too soft bed, cold at night and other reasons. 1. General treatment: Pay attention to rest and avoid overwork during the day. Don’t sleep on too soft or too hard mattress, choose a mattress with moderate hardness and softness. Pay attention to the warmth of the waist when sleeping at night. 2. Medication: Oral ibuprofen, celecoxib and other non-steroidal painkillers or methylcobalamin and other nutritive nerve medications can be used for treatment to relieve pain, numbness and other symptoms. You can also orally take ethylphenidate tablets and other muscle relaxing drugs to relieve muscle tension and spasm in the lower back. 3. Physiotherapy: Hot compresses, electric grills, ultrasound, and pelvic traction under professional guidance can be given to relieve pain. 4. Surgical treatment: If the above conservative treatment measures are ineffective, the symptoms are serious and affect daily life, surgical treatment is feasible, such as minimally invasive nucleus pulposus removal. If the pain of lumbar disc herniation persists at night, you should consult a doctor in time and take standardized treatment according to the doctor’s instructions, and not use medication on your own, so as to avoid delaying the condition.