Betalucil generic name for metoprolol, nifedipine and metoprolol can not be assessed which is better, under the guidance of the physician to choose the drug treatment according to the patient’s specific condition. Nifedipine is a calcium antagonist, through the dilation of blood vessels to reduce blood pressure, and can expand the coronary arteries, hypertension with coronary artery disease patients can take oral nifedipine treatment. Metoprolol is a β-receptor antagonist, which can be used in the treatment of coronary heart disease and hypertension, especially in patients with tachycardia; both metoprolol and nifedipine can be used in the treatment of hypertension, and both of them have different mechanisms of action, and the effect can not be directly evaluated, and the appropriate medication has to be chosen according to the patient’s condition. Nifedipine extended-release tablets are western prescription drugs, the adverse effects of the drug are dry stools, facial flushing, ankle edema, gingival hyperplasia, etc. Allergy to the drug components, severe aortic stenosis, patients taking rifampicin are prohibited. Metoprolol is a prescription drug that requires a prescription, the adverse effects of the drug are hypotension, dizziness, constipation, bradycardia, dyspnea, etc. It is contraindicated in patients with allergy to the components of the drug, bronchial asthma, severe bradycardia, uncontrolled heart failure, second- and third-degree atrioventricular block, cardiogenic shock. Nifedipine and metoprolol have their own advantages and disadvantages, and the drugs should be selected clinically under the guidance of a physician.