H. pylori overloads require a combination of medication, not only antibiotics, but also the destruction of the living environment of H. pylori. H. pylori is a common cause of gastric disorders. For people with recurrent gastric disorders, a breath test can be performed to help confirm the diagnosis, and for people with excessive indicators, medication should be used as soon as possible to eradicate the disease. H. pylori is a bacteria, so in the use of drugs is mainly the use of antibiotics to kill H. pylori, common antibiotics are clarithromycin, hydroxybenzyl penicillin, amoxicillin, metronidazole, levofloxacin, furazolidone and so on. The choice of antibiotics makes it possible to use a combination of two antibiotics, which will not only improve the chances of killing H. pylori, but also avoid the emergence of drug resistance of H. pylori. H. pylori is very demanding on the environment, this bacteria is mainly in the acidic environment to survive, in the environment is destroyed when the chances of killing will be higher. Therefore, antibiotics should be used along with drugs that inhibit gastric acid secretion to destroy the living environment of H. pylori, which mainly include lansoprazole, omeprazole, ranitidine, famotidine, etc. Some of the gastric mucosa has ulcerated surface, should also be combined with gastric mucosal protective agents for treatment, such as colloidal bismuth pectin, bismuth potassium citrate, aluminum thioglycollate, etc.