What are the consequences of leaving syphilis untreated for 20 years?

Syphilis has been untreated for more than twenty years, the disease may go from early syphilis to advanced syphilis, and the syphilis spirochete will invade the human body’s cardiovascular, cerebral nerves, bones, and other parts of the body, leading to a variety of cardiovascular and cerebrovascular lesions, as well as bone lesions, and so on.
Syphilis is a sexually transmitted disease caused by syphilis spirochete infection. Clinically, syphilis is generally categorized as Stage I, Stage II and Stage III syphilis. Stage I syphilis is usually characterized by the appearance of a hard chancre on the external genitalia and perianal area. Stage 2 syphilis is characterized by a variety of syphilitic rashes. Then if the patient is not treated aggressively in the early stages of syphilis, he or she will enter the late syphilis stage, which can present with cardiovascular syphilis, such as aortic insufficiency. Neurosyphilis, such as paralytic dementia, can also occur, and in severe cases, can be life-threatening.
For patients suffering from syphilis, it is recommended to go to a regular hospital for timely examination to avoid delaying the course of the disease, and under the guidance of the doctor to actively use medication.