It is possible that the baby may or may not have a congenital genetic problem after birth, which cannot be determined by Down’s syndrome screening alone. In this case, non-invasive DNA testing or amniocentesis is available. The non-invasive DNA prenatal testing technology only requires taking the venous blood of the pregnant woman, sequencing the free DNA fragments (including fetal free DNA) in the maternal peripheral plasma using the new generation DNA sequencing technology, and performing bioinformatics analysis on the sequencing results, from which the genetic information of the fetus can be obtained to detect whether the fetus has the three major chromosomal disorders. If the non-invasive DNA test is low risk, the pregnancy can continue.