The patient’s sudden inability to speak may be due to cerebrovascular disease and mental illness, as follows: 1. Cerebrovascular disease: generally caused by acute cerebrovascular disease, including acute cerebral infarction, transient ischemic attack, especially cerebrovascular lesions on the side of the dominant hemisphere, more likely to lead to patients with motor aphasia symptoms. 2. Mental illness: in addition to cerebrovascular disease, some mental illnesses, psychological and emotional factors, also can cause patients to appear suddenly unable to speak, such as schizophrenia, hysteria attacks, anxiety, depression and so on. Therefore, patients need to go to the neurology department in time to improve the cranial CT, cranial MRI and other examinations to clarify the cause and give targeted treatment for the cause. If the stroke is caused by acute ischemic stroke, the patient should be given timely treatment to improve circulation and nerve nutrition. If the stroke is due to mental or psychological factors, psychological comfort and medication should be given.