Gout may be caused by diseases, heredity and drugs. 1. Diseases: Erythrocytosis, acute and chronic leukemia, lymphoma, hemolytic anemia and other blood system diseases can be caused by a large number of intracellular nucleic acid decomposition and lead to excessive production of uric acid in the patient’s body, in addition to renal tubular disease, renal insufficiency and other renal disorders can be due to impaired excretion of uric acid and uric acid elevation and then gout. 2. Genetic: relevant research data show that about 10% to 20% of gout patients have a family history, in addition to hypoxanthine guanine phosphoribosyltransferase and other enzymes and metabolic defects may also lead to gout. 3. Drugs: Furosemide, tobacco acid, aspirin, tacrolimus, azathioprine, hydrochlorothiazide and other drugs can lead to increased reabsorption of uric acid through the renal tubules and reduce uric acid excretion. Gout may also be caused by other reasons, it is recommended that gout patients to the regular hospital rheumatology and immunology department for detailed consultation, follow the doctor’s instructions standardized treatment.