If the area of the ulcer is getting bigger, the cause of the ulcer must not be under control and it is recommended to go to the hospital for professional treatment in time. If the ulcer at the skin becomes larger, there is a deeper chemical rot need to be cleared, remove all the decayed tissue and disinfection, and then use with muscle-generating drugs to make the tissue self-grow. In the case of esophageal mucosa, fasting is recommended as soon as possible, especially in the case of gastroduodenal ulcers, which are increasing in size and are prone to acute bleeding from the upper gastrointestinal tract, in addition to pain. Acute bleeding is likely to be life-threatening if not controlled in time, as the lower layer of the mucosal muscle is heavily vascularized in the gastrointestinal tract, and prompt professional treatment is required, and in severe cases, gastric perforation repair and duodenal perforation repair can be performed.