Severe pseudo-fatty dystrophy, almost only seen in boys, if the mother is a gene carrier, 50% of male offspring, often starting at the age of 2-8 years, the initial feeling of walking clumsily, easy to fall, not able to run and climb stairs, standing spinal cord convex, the abdomen out, the two feet spread out, walking slowly swaying, showing a special “duck step” gait. When the patient is lying on his back, it is very difficult for him to stand up, so he must first turn over and lie on his back, and then climb over his knees with both hands, and then gradually stand up with his hands upward (Gower’s sign). It can also be seen in the proximal limb muscles, quadriceps and brachialis muscles. How to effectively prevent and treat Severe Pseudohypertrophic Massive Dystrophy? 1. Genetic counseling and testing for carriers. Eugenics is a positive and effective way to prevent the development of this disease. People with a family history of muscular dystrophy should see a specialist for a detailed genealogical analysis. Among the four types of muscular dystrophy, Duchenne muscular dystrophy (DMD) with pseudohypertrophy is the most dangerous to children’s health. Therefore, the detection of carriers is of great significance to the prevention of Duchenne type (DMD) and marital status. 2.Test for creatine phosphokinase (CPK). Creatine phosphokinase (CPK) in the serum of patients with pseudohypertrophy of myotonic dystrophy is increased, and the measurement of the activity can detect the suspected carriers of some disease genes. Especially in Duchenne patients, about 60-80% of certain carriers and highly suspected carriers have increased creatine phosphokinase activity. 3. Prenatal sex determination. Prenatal determination of gender is important for high-risk fetuses in families with myotonic dystrophy. Female carriers, male patients with myotonic dystrophy with Duchenne type (DMD) characteristics, so suspected Duchenne type (DMD) carriers of maternal late pregnancy should be done amniotic fluid examination, in order to detect the gene locus with or without mutations; Duchenne Hin (DMD) carriers pregnant women to determine for the boy should be first fetoscope fetal blood, check creatine phosphate kinase (CPK) or serum myoglobin (Mb) before deciding whether or not to terminate. ) before deciding whether to terminate the pregnancy. Treatment 1, physical therapy: clinical practice has shown that appropriate physical exercise and full movement of all joints, although not a cure for the disease, can at least delay the onset of more severe muscle atrophy, muscle weakness and joint contractures. Therefore, encourage patients to do as much activity in the treatment of this disease plays a more important role. 2, massage: massage for the massage of the disease generally include appropriate techniques to stimulate the relevant meridian points, play the role of adjusting the function of the organism and internal organs; and to assist the patient to the joints for the necessary functional exercise to delay the occurrence of muscle atrophy and prevent the patient’s joints from contracture, etc. In many cases, the latter than the former. In many cases, the latter is more important than the former. 3, acupuncture: strictly speaking, patients with this disease should be careful with acupuncture treatment, especially to be careful with body acupuncture treatment. In the necessary application of acupuncture treatment, must pay attention to master the stimulation intensity of acupuncture, patients with this disease should not use strong stimulation. 4.Targeted therapy: Nerve-targeted repair therapy makes the nerve growth factor act on the damaged area through intervention. It activates dormant nerve cells, realizes self-differentiation and renewal of nerve cells, replaces damaged and dead nerve cells, rebuilds nerve circuits, and promotes organ development again.