Bipolar disorder is characterized by recurrent and alternating episodes of mania and depression, which in Chinese medicine belongs to the category of depression, and can be treated with the addition and subtraction of Puanxuan. In Chinese medicine, it is generally believed that depression is the result of emotional discomfort, liver qi stagnation, loss of spleen health, loss of nourishment for the heart, etc. The pathogenesis of depression is stagnation of qi, and dysfunction of yin and yang in the internal organs, which should be treated by dredging the liver and relieving depression, and supplemented by strengthening the spleen and nourishing the heart (strengthening the spleen and stomach, and replenishing and nourishing the heart and spirit). Free and Easy is composed of Chai Hu, Mentha piperita, Paeonia lactiflora, Angelica sinensis, Poria, Atractylodes macrocephala, and Cannonball Ginger. Among them, Chai Hu is the principal herb, which can relieve the liver and depression. White peony and Angelica sinensis are the ministerial herbs, which can tonify liver blood and help the liver. Atractylodes macrocephala and Poria are the supporting herbs, atractylodes macrocephala can dry dampness and strengthen the spleen, Poria can strengthen the spleen and promote dampness. Peppermint is also used as an adjuvant as it can disperse stagnant Qi and penetrate heat in the liver meridian, and ginger can warm the stomach and harmonize the middle of the body. When suffering from bipolar disorder, the patient’s family should pay attention to guidance, and seek professional medical treatment as soon as possible, the use of traditional Chinese medicine need to be identified.