Lung infection after craniotomy has been fever first need to be cooled down, and then the use of antibiotics for treatment, the situation is serious patients also need to suction out the sputum. After craniotomy lung infection has been fever, need to first of all to lower the patient’s heat treatment, body temperature is lower than 38.5 ℃, you can use physical cooling for cooling, if higher than 38 degrees 5 or more, you need to use the use of ibuprofen, acetaminophen and other drugs to lower the temperature of the treatment. While cooling down the temperature, we should culture the bacteria in the patient’s sputum and choose the most effective antibiotic drugs for treatment, such as roxithromycin, doxycycline and so on. At the same time, we should do a good job of patient care to avoid the accumulation of sputum in the lungs can be used to nebulize sputum suction, shock expectoration method for expectoration treatment. If the sputum can not be discharged in time, bronchoscopy is needed to suck out the sputum. Lung infection after craniotomy, must be treated in time to avoid aggravation of the condition, affecting the patient’s life and health.