Girls’ underarm sweating with sour sweat odor may be caused by physiological factors, such as poor hygiene habits, etc.; it may also be caused by pathological factors, such as fox odor. Patients need to be dealt with according to the cause of the disease through general treatment, drug treatment, surgical treatment and other methods. 1. Physiological factors: if the patient has bad hygiene habits, such as not bathing for a long time, not changing clothes, etc., so that sweat accumulates in the armpit, odor. This situation does not require special treatment, through timely change of clothing, timely bathing will disappear on its own. 2. Pathological factors: common diseases such as fox odor, the odor of fox odor is caused by bacterial decomposition of the secretions of the top secretory glands in the armpits, the typical symptom is a pungent odor in the armpits, which is more pronounced in summer or after exercise. Patients with mild symptoms can improve by bathing and changing clothes regularly; they can also use formaldehyde solution, aluminum chloride anhydrous ethanol solution and other medications under the guidance of a doctor to alleviate the problem. Severe symptoms, can follow the doctor’s advice through surgical treatment, the axilla top secretion of sweat glands and the surrounding tissue removal, or the use of botulinum toxin A to inhibit the secretion of the top secretion of sweat glands, to achieve the purpose of removing the odor. It is recommended that girls who sweat underarms and have a sour sweaty odor go to a regular hospital in a timely manner, to clarify the cause of the disease, and actively cooperate with the doctor to carry out the appropriate treatment.