Patients with high blood glucose and constipation should control their blood glucose first. Diabetic patients are prone to constipation, so when blood glucose is high, they can use polyethylene glycol and mannitol for laxative purposes, and at the same time, they should drink a lot of water. The above drugs can not be used easily, should be used under medical treatment, if a large number of use or prolonged use will lead to patients with water electrolyte imbalance. Clinically, senna can quickly defecate, but it can cause a lot of diarrhea, resulting in an imbalance of water-electrolyte balance in the patient’s body or hypokalemia. Therefore, patients with high blood sugar and constipation should usually improve the intake of dietary fiber, eat more leafy greens, coarse grains, and usually develop good defecation habits.