There is no such thing as the best treatment for ligament sprains. Ligament sprains need to choose the appropriate treatment according to the severity of the injury, such as general treatment, physical therapy, drug therapy, surgical treatment and so on. 1. General treatment: After ligament sprain, we should pay attention to rest and braking, and can elevate the affected limb to promote blood return. 2. Physical therapy: within 72 hours of acute injury, cold compresses can be applied to the affected area; hot compresses can be applied during the 72-hour recovery period after the injury; physical therapy can reduce inflammation and relieve swelling and pain. 3. Medication: Commonly used drugs are non-steroidal anti-inflammatory drugs, such as diclofenac sodium, celecoxib, etc., which can play a role in reducing inflammation and relieving swelling and pain. 4. Surgery: If the ligament sprain is relatively serious and there is a ligament tear, it can be fixed with a plaster or brace for 3~4 weeks. If there is a rupture of the ligament, surgical treatment is needed for repair and reconstruction. After the ligament sprain, if the pain and swelling is obvious, the activity is affected, you should go to the hospital in time to improve the examination to determine the condition, and then choose the targeted treatment method. The above drugs need to be applied under the guidance of a physician.