Generally speaking, there are the following major categories of oral medications for diabetes: the first is sulfonylureas, the second is biguanides, such as metformin, which is a biguanide hypoglycemic drug, which is indicated for obese patients with type 2 diabetes. The third is an alpha-glucosidase inhibitor, which is often referred to as voglibose or bactrim, acarbose. The fourth is an insulin sensitizer, but it should not be used in patients with cardiac insufficiency. The fifth one is a glinide type insulin secretagogue, such as Repaglinide and Naglinide, which can accelerate the secretion of insulin and be taken orally immediately before meals and not without meals. But the specific application of which drug, it is recommended that the patient under the guidance of the doctor, combined with the patient’s underlying disease, liver and kidney function, and blood sugar situation to choose a comprehensive.