Valsartan is an antihypertensive drug. The combination of this drug with which medication has the least side effects will depend on the patient’s specific situation. The drug itself is among the lesser side effects among antihypertensive drugs. Common adverse reactions include dizziness, headache, bloating, diarrhea, and cough. It is mainly suitable for patients with mild or moderate essential hypertension. If the effect is not satisfactory after using this drug, it can be used with beta receptor inhibitors, such as metoprolol succinate extended-release tablets; it can also be used with calcium antagonists, such as nifedipine controlled-release tablets. All of the above drugs should be used under doctor’s supervision. If any discomfort occurs, you should consult a doctor immediately to avoid delaying the condition.