The main ingredient of Eusemide is Drospirenone Ethinyl Estradiol Tablets. The recommended usage is to start taking the pill on the 1st day of menstruation, but it is not necessary to start taking the pill on the 1st day, you can also start taking the pill on the 2nd-5th day of menstruation, which is the normal method of contraception. However, it is not recommended to take the pill after more than 5 days because Eusebio will contain estrogen and progestin, which will mimic the hormonal cycle of the human ovaries, so it is not recommended to take Eusebio orally if it is more than 5 days. However, there are some special cases where you can take Eusemide orally. If you are switching to Eusemide from another combination contraceptive, you can start taking Eusemide orally on the second day after the other combination contraceptive is finished. Also if it is a progestogen-only method, you can take Eusebio by mouth at any time, so it needs to be decided on a case-by-case basis.