When the hole oozes fluid after the drain is removed, the hole can be closed with a second-stage suture or pressure dressing. Drainage tubes are used in a variety of surgical procedures, and at the same time, there are various types of drainage tubes, the main role of which includes drainage of surgical site fluids, therapeutic drainage and so on. When there is no or little drainage in the drain, the criteria for extubation for the relevant surgery have been met and extubation is required. Commonly, such as thoracic drainage tubes used in thoracic surgery, when pulling out the tube, it is necessary to apply pressure bandage to the hole, and use the chest strap for external fixation of the thorax to prevent the effusion of fluid, and when there is still oozing of fluid from the hole, a second-stage surgery can be carried out to close the hole with sutures and seal the hole. If a cerebrospinal fluid drain is used for brain surgery, the hole is usually sutured directly and then pressure bandaged when the drain is removed. Fluid leakage from drainage tube holes is more common in clinical practice, and it is recommended to seek medical attention and follow the guidance of a medical professional.