Ankylosing spondylitis patients with joint limitation can be treated with medication and surgery. Drug treatment: some of the joint movement limitation is caused by inflammation, then active anti-inflammatory treatment can get very good results. Drugs are mainly anti-rheumatic drugs such as sulfasalazine, non-steroidal drugs such as celecoxib, and biologics such as adalimumab, etc., which can alleviate symptoms and inhibit bone destruction. Surgery: If the symptoms of joint limitation are severe or even if there is severe deformity of the joints, surgery can be performed after evaluation by a physician to improve joint function. It is recommended that ankylosing spondylitis patients with joint limitation go to the rheumatology department of a regular hospital as soon as possible and follow the doctor’s instructions for treatment.