The worsening of a tickling cough at night is often considered to be related to vagal excitation, cough variant asthma, reflux pharyngitis, etc. The following are some of the symptoms of this condition 1. Vagus nerve excitation: at night, the vagus nerve excitability is higher, contracting the bronchial smooth muscle, enhancing the sensitivity of the airway, which in turn causes the worsening of the scratchy throat and cough; 2. Cough variant asthma: the onset of the patient is related to contact with allergens, especially during sleep, exposure to formaldehyde and irritant gases from furniture and allergens such as mites on bedding, sheets, pillows and so on, which triggers a dry and itchy throat and aggravated cough. 3. Reflux pharyngitis: patients with reflux pharyngitis, especially at night when lying down to sleep, reflux is more serious, resulting in gastric acid stimulation of the mucous membrane in the throat, resulting in itchy throat, cough aggravation. Itchy throat, cough aggravated at night is recommended to consult a doctor in a timely manner, under the guidance of a specialist physician to specify the cause of the standardized treatment.