Headaches caused by foramen ovale insufficiency present with throbbing headache symptoms on one or both sides. Headaches due to patent foramen ovale are usually migraines. The onset may be characterized by a throbbing headache on one or both sides, with paroxysmal exacerbation. Some patients may experience blackness in front of the eyes, accompanied by dizziness, nausea, vomiting, blurred vision and other symptoms, and the symptoms of headache will be relatively relieved after vomiting. If the foramen ovale is not closed, it may lead to abnormal blood flow in the left atrium and right atrium, and blood shunt occurs. Metabolites from the body can easily enter the arterial blood with the shunt, and can enter the skull through the blood-brain barrier, thus causing headache symptoms. Non-steroidal anti-inflammatory drugs such as ibuprofen and diclofenac can be used for treatment to relieve the pain, and olecranon repair is feasible if necessary. Headache patients should seek prompt medical attention to clarify the diagnosis under the guidance of the doctor. If the diagnosis is confirmed to be caused by the unclosed foramen ovale, targeted treatment should be carried out under the guidance of the doctor to alleviate the symptoms.