Four Substances Cream can regulate irregular menstruation due to blood deficiency and is suitable for those with scanty menstrual flow and pale color. It is not suitable for all menstrual disorders. Four Substances Cream is derived from Four Substances Soup of “Immortal License for Treating Injuries and Continuing Fracture Secret Formula”. Four Substances Cream is composed of white peony, angelica sinensis, chuanxiong rhizoma, and ripened rhizoma. It has the effect of regulating menstruation and nourishing blood. It is used for treating low menstrual flow caused by blood deficiency, pale menstrual blood, dizziness and fatigue, and bloodless face and lips. The adverse reactions of Four Substances Cream are not clear. Four Substances Cream is contraindicated in pregnant women and diabetic patients. The medicine should not be used by those with menstrual chest and hypochondrium distension and pain or with blood clots accompanied by abdominal pain. Avoid eating cold and spicy food during the period of taking the medicine. If you feel unwell, you should go to a regular medical institution in time, do not blindly self-medication, so as not to delay the condition.