Low mean platelet distribution width may be caused by normal physiological factors, aplastic anemia, chronic granulocytic leukemia, etc. It can be improved by medication and surgery. 1. Normal physiological factors: the size of platelets in human body is basically the same, low platelet mean distribution width, but the number of platelets and other indicators in the blood routine are not abnormal, generally it is a normal phenomenon, and no special treatment is needed. 2. aplastic anemia: aplastic anemia is mainly caused by the decline of bone marrow hematopoietic function, abnormal bone marrow hematopoietic function, resulting in a decrease in the number of platelets generated, its volume may also be reduced accordingly, can use stanozolol and other drugs that can promote bone marrow hematopoiesis to improve, if the condition is more serious, can be used to rebuild the body’s hematopoietic function of bone marrow hematopoietic stem cell transplantation. 3. Chronic granulocytic leukemia: Chronic granulocytic leukemia is mainly caused by malignant proliferation of hematopoietic stem cells, which can cause thrombocytosis and low platelet width, etc. Drugs such as Dasatinib tablets can be used to inhibit the malignant proliferation of hematopoietic stem cells, and if necessary, bone marrow reconstruction can be carried out through transplantation of hematopoietic stem cells, so as to improve the situation of low platelet width. In case of low platelet width, you should actively cooperate with your doctor to do the appropriate blood tests to clarify the cause of the disease and follow the doctor’s instructions.