In general, granular medicines can be swallowed directly and will not affect the efficacy. Common granular drugs (such as cold clear granules) can be swallowed directly under normal circumstances, can also be taken with warm water, will not affect the absorption and efficacy of the drug. However, it is recommended that you consult your doctor for advice on how to take the medication according to your condition. But except for some special circumstances, such as infants and young children to take granular drugs recommended with warm water to avoid drying or small particles of drugs caused by choking; and for some obvious labeling of drugs with boiling water is not recommended to be swallowed directly, so as not to affect the efficacy of the drug, such as traditional Chinese medicine granules are often required to use warm water, more conducive to the absorption and utilization of drugs. Therefore, the general particles of drugs can be swallowed directly. But also need to be determined on a case-by-case basis, if there are conditions under the circumstances try to take with water.