There is no essential difference between domestic Tenofovir and imported Tenofovir, and you can’t say one-sidedly which one is better. Tenofovir is used to treat chronic HBV infection and HIV infection. Tenofovir is used in combination with other reverse transcriptase inhibitors for the treatment of chronic hepatitis B and HIV-1 infection. There are differences in the dosage of this product between different sizes and dosage forms, so read the specific instructions for taking the drug or take it as directed by your doctor. The drug needs to be taken with food, and the dosage used is not allowed to exceed the recommended dose. There are also certain side effects associated with taking tenofovir, such as generalized weakness, mild to moderate gastrointestinal discomfort, fat accumulation and redistribution, and may even cause hepatomegaly and lactic acidosis associated with steatosis. The drug is contraindicated in patients who are allergic to tenofovir, tenofovir ester tablets, or any of the ingredients in tenofovir ester. Tenofovir must be taken under the guidance of a doctor, not without authorization, to avoid adverse reactions.