The process of blood clot changes after tooth extraction includes five main processes, including blood clot formation, granulation tissue formation, connective tissue replacing granulation tissue, fibrous odontoblasts replacing connective tissue, and mature bone tissue generation. 1. Formation of blood clot: After tooth extraction, the apical blood vessels and periodontal tissues are torn, resulting in bleeding in the alveolar socket. The bleeding stops after about 15~30 minutes, and the blood clot forms to close the wound and help it heal. 2. Formation of granulation tissue: A few hours after the extraction, the gum tissue shrinks to protect the blood clot and aid in wound healing. About 24 hours after extraction, the endothelial cells of the alveolar blood vessels proliferate to form a capillary network, and in about 7 days, granulation tissue replaces the blood clot. 3. Connective tissue replaces granulation tissue: 3~4 days after tooth extraction, more mature connective tissue will appear, thus replacing the granulation tissue. 4. Fibrous bone replaces connective tissue: about 38 days after extraction, 2/3 of the socket will be filled with fibrous bone, which replaces connective tissue. 5. Mature Bone Tissue Generation: About 40 days after extraction, mature bone will slowly form in the healing area until mature bone tissue is generated. You should not brush your teeth or rinse your mouth or lick the wound with your tongue for 24 hours after the extraction. After about 2 hours, when the blood clot is well formed, you can eat, and it is recommended to eat liquid or soft food.